| Sem. | Fecha | Visitante | Local | G/P/E | G | P | E | G (H) | P (H) | E (H) | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2021-09-12 | Miami | 17 | 16 | New England | G | 1 | 0 | 0 | 488 | 398 | 4 | |
| 2 | 2021-09-19 | Buffalo | 35 | 0 | Miami | P | 1 | 1 | 0 | 488 | 399 | 4 | |
| 3 | 2021-09-26 | Miami | 28 | 31 TE | Las Vegas | P | 1 | 2 | 0 | 488 | 400 | 4 | |
| 4 | 2021-10-03 | Indianapolis | 27 | 17 | Miami | P | 1 | 3 | 0 | 488 | 401 | 4 | |
| 5 | 2021-10-10 | Miami | 17 | 45 | Tampa Bay | P | 1 | 4 | 0 | 488 | 402 | 4 | |
| 6 | 2021-10-17 | Miami | 20 | 23 | Jacksonville (Lon) | P | 1 | 5 | 0 | 488 | 403 | 4 | |
| 7 | 2021-10-24 | Atlanta | 30 | 28 | Miami | P | 1 | 6 | 0 | 488 | 404 | 4 | |
| 8 | 2021-10-31 | Miami | 11 | 26 | Buffalo | P | 1 | 7 | 0 | 488 | 405 | 4 | |
| 9 | 2021-11-07 | Houston | 9 | 17 | Miami | G | 2 | 7 | 0 | 489 | 405 | 4 | |
| 10 | 2021-11-11 | Baltimore | 10 | 22 | Miami | G | 3 | 7 | 0 | 490 | 405 | 4 | |
| 11 | 2021-11-21 | Miami | 24 | 17 | NY Jets | G | 4 | 7 | 0 | 491 | 405 | 4 | |
| 12 | 2021-11-28 | Carolina | 10 | 33 | Miami | G | 5 | 7 | 0 | 492 | 405 | 4 | |
| 13 | 2021-12-05 | NY Giants | 9 | 20 | Miami | G | 6 | 7 | 0 | 493 | 405 | 4 | |
| 14 | 2021-12-12 | DESCANSO | |||||||||||
| 15 | 2021-12-19 | NY Jets | 24 | 31 | Miami | G | 7 | 7 | 0 | 494 | 405 | 4 | |
| 16 | 2021-12-27 | Miami | 20 | 3 | New Orleans | G | 8 | 7 | 0 | 495 | 405 | 4 | |
| 17 | 2022-01-02 | Miami | 3 | 34 | Tennessee | P | 8 | 8 | 0 | 495 | 406 | 4 | |
| 18 | 2022-01-09 | New England | 24 | 33 | Miami | G | 9 | 8 | 0 | 496 | 406 | 4 |
Lon.: Juego en Tottenham Hotspur Stadium en Londres, Inglaterra.