| No. | Jugador | Fumbles | Años | Equipo(s) |
|---|---|---|---|---|
| 1 | Robert Mathis | 52 | 2003-2016 | Ind |
| 2 | Julius Peppers+ | 51 | 2002-2018 | Car, Chi, GB |
| 3 | John Abraham | 48 | 2000-2014 | NYJ, Atl, Az |
| Chris Doleman+ | 48 | 1985-1999 | Min, Atl, SF | |
| Jason Taylor+ | 48 | 1997-2011 | Mia, Was, NYJ | |
| 6 | Dwight Freeney+ | 47 | 2002-2017 | Ind, SD, Az, Atl, Sea, Det |
| 7 | Bruce Smith+ | 45 | 1985-2003 | Buf, Was |
| 8 | Rickey Jackson+ | 44 | 1981-1995 | NO, SF |
| Derrick Thomas+ | 44 | 1989-1999 | KC | |
| Charles Tillman | 44 | 2003-2015 | Chi, Car | |
| 11 | Lawrence Taylor+ | 41 | 1981-1993 | NYG |
| 12 | Brian Dawkins+ | 39 | 1996-2011 | Phi, Den |
| Terrell Suggs | 39 | 2003-2019 | Bal, Az, KC | |
| Pat Swilling | 39 | 1986-1998 | NO, Det, Oak | |
| 15 | Greg Lloyd | 38 | 1988-1998 | Pit, Car |
| 16 | Richard Dent+ | 37 | 1983-1997 | Chi, SF, Ind, Phi |
| Simeon Rice | 37 | 1996-2007 | Az, TB, Den, Ind | |
| 18 | Khalil Mack | 36 | 2014- | Oak, Chi, LAC |
| T.J. Watt | 36 | 2017- | Pit | |
| 20 | Osi Umenyiora | 35 | 2003-2014 | NYG, Atl |
| DeMarcus Ware+ | 35 | 2005-2016 | Dal, Den | |
| 22 | James Harrison | 34 | 2002-2017 | Pit, Cin, NE |
| Chandler Jones | 34 | 2012-2022 | NE, Az, LV | |
| Neil Smith | 34 | 1988-2000 | KC, Den, SD | |
| Charles Woodson+ | 34 | 1998-2015 | Raid, GB | |
| 26 | Lavonte David | 33 | 2012-2025 | TB |
| Leonard Little | 33 | 1998-2009 | SLR | |
| Reggie White+ | 33 | 1985-2000 | Phi, GB, Car | |
| 29 | Mike Douglass | 32 | 1978-1986 | GB, SD |
| Tamba Hali | 32 | 2006-2017 | KC | |
| Robert Quinn | 32 | 2011-2022 | LAR, Mia, Dal, Chi, Phi | |
| 32 | Jared Allen+ | 31 | 2004-2015 | KC, Min, Chi, Car |
| 33 | Jacob Green | 30 | 1980-1992 | Sea, SF |
| Greg Townsend | 30 | 1983-1997 | Raid, Phi | |
| 35 | Cliff Avril | 29 | 2008-2017 | Det, Sea |
| Tony Brackens | 29 | 1996-2003 | Jax | |
| Seth Joyner | 29 | 1986-1998 | Phi, Az, GB, Den | |
| 38 | Trace Armstrong | 28 | 1989-2003 | Chi, Mia, Raid |
| Cornelius Bennett | 28 | 1987-2000 | Buf, Atl, Ind | |
| Mo Lewis | 28 | 1991-2003 | NYJ | |
| John Randle+ | 28 | 1990-2003 | Min, Sea | |
| 42 | Kevin Greene+ | 27 | 1985-1999 | LAR, Pit, Car, SF |
| Jevon Kearse | 27 | 1999-2009 | Ten, Phi | |
| Von Miller | 27 | 2011- | Den, LAR, Buf, Was | |
| Leslie O’Neal | 27 | 1986-1999 | SD, SLR, KC | |
| J.J. Watt | 27 | 2011-2022 | Hou, Az | |
| 47 | Nesby Glasgow | 26 | 1979-1992 | Ind, Sea |
| Ryan Kerrigan | 26 | 2011-2021 | Was, Phi | |
| Joey Porter | 26 | 1999-2011 | Pit, Mia, Az | |
| 50 | Derrick Brooks+ | 25 | 1995-2008 | TB |
| Simon Fletcher | 25 | 1985-1995 | Den | |
| Charles Haley+ | 25 | 1986-1999 | SF, Dal | |
| Ken Harvey | 25 | 1988-1998 | Pho, Was | |
| Robert Porcher | 25 | 1992-2003 | Det | |
| Clyde Simmons | 25 | 1986-2000 | Phi, Az, Jax, Cin, Chi |
