| 1 | George Blanda (Hou.Oilers) | 42 | 1962 |
| 2 | Vinny Testaverde (TB) | 35 | 1988 |
| 3 | Frank Tripucka (Den) | 34 | 1960 |
| 4 | John Hadl (SD) | 32 | 1968 |
| | Fran Tarkenton (Min) | 32 | 1978 |
| 6 | Sid Luckman (Chi) | 31 | 1947 |
| 7 | George Blanda (Hou.Oilers) | 30 | 1965 |
| | Al Dorow (NY.Titans) | 30 | 1961 |
| | Jim Hart (StL.Cardinals) | 30 | 1967 |
| | Ken Stabler (Oak) | 30 | 1978 |
| | Richard Todd (NYJ) | 30 | 1980 |
| | Jameis Winston (TB) | 30 | 2019 |
| 13 | Lynn Dickey (GB) | 29 | 1983 |
| | Brett Favre (GB) | 29 | 2005 |
| 15 | Peyton Manning (Ind) | 28 | 1998 |
| | Joe Namath (NYJ) | 28 | 1967 |
| | Joe Namath (NYJ) | 28 | 1975 |
| | Ken Stabler (Hou.Oilers) | 28 | 1980 |
| | Y.A. Tittle (SF) | 28 | 1955 |
| 20 | George Blanda (Hou.Oilers) | 27 | 1964 |
| | Drew Bledsoe (NE) | 27 | 1994 |
| | Eli Manning (NYG) | 27 | 2013 |
| | Joe Namath (NYJ) | 27 | 1966 |
| | Babe Parilli (Bos.Patriots) | 27 | 1964 |
| | Bud Schwenk (Chi.Cardinals) | 27 | 1942 |
| | Norm Snead (Was) | 27 | 1963 |
| | Jim Zorn (Sea) | 27 | 1976 |
| 28 | Jay Cutler (Chi) | 26 | 2009 |
| | Al Dorow (NY.Titans) | 26 | 1960 |
| | Jim Finks (Pit) | 26 | 1955 |
| | John Hadl (SD) | 26 | 1972 |
| | Sonny Jurgensen (Phi) | 26 | 1962 |
| | Jack Kemp (Buf) | 26 | 1964 |
| | Jack Kemp (Buf) | 26 | 1967 |
| | Tommy Kramer (Min) | 26 | 1985 |
| | Warren Moon (Hou.Oilers) | 26 | 1986 |
| | Babe Parilli (Bos.Patriots) | 26 | 1965 |
| | Dennis Shaw (Buf) | 26 | 1971 |
| | Brian Sipe (Cle) | 26 | 1979 |
| | Richard Todd (NYJ) | 26 | 1983 |
| 41 | George Blanda (Hou.Oilers) | 25 | 1963 |
| | Terry Bradshaw (Pit) | 25 | 1979 |
| | Charlie Conerly (NYG) | 25 | 1953 |
| | Lynn Dickey (GB) | 25 | 1980 |
| | Joe Ferguson (Buf) | 25 | 1983 |
| | Frank Filchock (NYG) | 25 | 1946 |
| | John Hadl (SD) | 25 | 1971 |
| | Bobby Hebert (Atl) | 25 | 1996 |
| | Jack Kemp (LAC) | 25 | 1960 |
| | Daryle Lamonica (Oak) | 25 | 1969 |
| | Eddie LeBaron (Dal) | 25 | 1960 |
| | Eli Manning (NYG) | 25 | 2010 |
| | Jim Plunkett (NE) | 25 | 1972 |
| | Brian Sipe (Cle) | 25 | 1981 |
| | Fran Tarkenton (Min) | 25 | 1962 |
| | Vinny Testaverde (NYJ) | 25 | 2000 |
| | Frank Tripucka (Den) | 25 | 1962 |
| | Danny White (Dal) | 25 | 1980 |
| | Dick Wood (NYJ) | 25 | 1964 |
| 60 | Terry Bradshaw (Pit) | 24 | 1970 |
| | John Brodie (SF) | 24 | 1971 |
| | Brett Favre (GB) | 24 | 1993 |
| | Joe Ferguson (Buf) | 24 | 1977 |
| | Dan Fouts (SD) | 24 | 1979 |
| | Dan Fouts (SD) | 24 | 1980 |
| | Otto Graham (Cle) | 24 | 1952 |
| | Trent Green (KC) | 24 | 2001 |
| | John Hadl (SD) | 24 | 1962 |
| | Jim Hardy (Chi.Cardinals) | 24 | 1950 |
| | Charley Johnson (StL.Cardinals) | 24 | 1964 |
| | Sonny Jurgensen (Phi) | 24 | 1961 |
| | Tommy Kramer (Min) | 24 | 1979 |
| | Tommy Kramer (Min) | 24 | 1981 |
| | Dave Krieg (Sea) | 24 | 1984 |
| | Babe Parilli (Bos.Patriots) | 24 | 1963 |
| | Babe Parilli (Bos.Patriots) | 24 | 1967 |
| | Jake Plummer (Az) | 24 | 1999 |
| | George Ratterman (NY.Yanks) | 24 | 1950 |
| | Tobin Rote (GB) | 24 | 1950 |
| | Norm Snead (Phi) | 24 | 1967 |
| | Ken Stabler (Oak) | 24 | 1975 |
| | Johnny Unitas (Bal.Colts) | 24 | 1960 |
| | Johnny Unitas (Bal.Colts) | 24 | 1961 |
| | Johnny Unitas (Bal.Colts) | 24 | 1966 |
| | Billy Wade (Chi) | 24 | 1962 |
| | Bob Waterfield (LAR) | 24 | 1949 |
| | Doug Williams (TB) | 24 | 1979 |
| 88 | Frankie Albert (SF) | 23 | 1950 |
| | Steve Bartkowski (Atl) | 23 | 1981 |
| | Sammy Baugh (Was) | 23 | 1948 |
| | George Blanda (Chi) | 23 | 1953 |
| | Adrian Burk (Phi) | 23 | 1951 |
| | Daunte Culpepper (Min) | 23 | 2002 |
| | Cotton Davidson (Dal.Texans) | 23 | 1961 |
| | Cotton Davidson (Dal.Texans/Oak) | 23 | 1962 |
| | John Elway (Den) | 23 | 1985 |
| | Brett Favre (GB) | 23 | 1998 |
| | Brett Favre (GB) | 23 | 1999 |
| | Vince Ferragamo (LAR) | 23 | 1983 |
| | Ryan Fitzpatrick (Buf) | 23 | 2011 |
| | Steve Grogan (NE) | 23 | 1978 |
| | Jeff Komlo (Det) | 23 | 1979 |
| | Tommy Kramer (Min) | 23 | 1980 |
| | Bobby Layne (Det) | 23 | 1951 |
| | Peyton Manning (Ind) | 23 | 2001 |
| | Dan Marino (Mia) | 23 | 1986 |
| | Dan Marino (Mia) | 23 | 1988 |
| | Paul McDonald (Cle) | 23 | 1984 |
| | Bill Nelsen (Cle) | 23 | 1971 |
| | Joe Pisarcik (NYG) | 23 | 1978 |
| | Ben Roethlisberger (Pit) | 23 | 2006 |
| | Brian Sipe (Cle) | 23 | 1983 |
| | Norm Snead (Phi) | 23 | 1969 |
| | Johnny Unitas (Bal.Colts) | 23 | 1962 |
| | Danny White (Dal) | 23 | 1983 |
| | Randy Wright (GB) | 23 | 1986 |
| 117 | Ken Anderson (Cin) | 22 | 1978 |
| | George Blanda (Hou.Oilers) | 22 | 1960 |
| | George Blanda (Hou.Oilers) | 22 | 1961 |
| | Terry Bradshaw (Pit) | 22 | 1971 |
| | Terry Bradshaw (Pit) | 22 | 1980 |
| | Drew Brees (NO) | 22 | 2010 |
| | John Brodie (SF) | 22 | 1966 |
| | Aaron Brooks (NO) | 22 | 2001 |
| | Scott Brunner (NYG) | 22 | 1983 |
| | Marc Bulger (StL.Rams) | 22 | 2003 |
| | Paul Christman (Chi.Cardinals) | 22 | 1947 |
| | Charlie Conerly (NYG) | 22 | 1951 |
| | Steve DeBerg (SF) | 22 | 1978 |
| | Boomer Esiason (Cin) | 22 | 1990 |
| | Brett Favre (NYJ) | 22 | 2008 |
| | Joe Flacco (Bal) | 22 | 2013 |
| | Dan Fouts (SD) | 22 | 1986 |
| | Josh Freeman (TB) | 22 | 2011 |
| | Paul Governali (Bos.Yanks/NYG) | 22 | 1947 |
| | Steve Grogan (NE) | 22 | 1980 |
| | John Hadl (SD) | 22 | 1967 |
| | Joey Harrington (Det) | 22 | 2003 |
| | George Herring (Den) | 22 | 1961 |
| | Jack Kemp (SD) | 22 | 1961 |
| | Jack Kemp (Buf) | 22 | 1969 |
| | Jon Kitna (Cin) | 22 | 2001 |
| | Jon Kitna (Det) | 22 | 2006 |
| | DeShone Kizer (Cle) | 22 | 2017 |
| | Johnny Lujack (Chi) | 22 | 1949 |
| | Dan Marino (Mia) | 22 | 1989 |
| | Lamar McHan (Chi.Cardinals) | 22 | 1954 |
| | Joe Namath (NYJ) | 22 | 1974 |
| | Carson Palmer (Az) | 22 | 2013 |
| | Jim Plunkett (NE) | 22 | 1974 |
| | George Ratterman (Buf) | 22 | 1948 |
| | Jay Schroeder (Was) | 22 | 1986 |
| | Phil Simms (NYG) | 22 | 1986 |
| | Norm Snead (Was) | 22 | 1961 |
| | Norm Snead (Was) | 22 | 1962 |
| | Norm Snead (NYG) | 22 | 1973 |
| | Ken Stabler (Oak) | 22 | 1979 |
| | Vinny Testaverde (TB) | 22 | 1989 |
| | Tommy Thompson (Phi) | 22 | 1950 |
| | Y.A. Tittle (NYG) | 22 | 1964 |
| | Richard Todd (NYJ) | 22 | 1979 |
| | Billy Wade (LAR) | 22 | 1958 |
| | Kurt Warner (StL.Rams) | 22 | 2001 |
| 164 | Pete Beathard (Hou.Oilers) | 21 | 1969 |
| | George Blanda (Hou.Oilers) | 21 | 1966 |
| | Drew Bledsoe (NE) | 21 | 1999 |
| | Zeke Bratkowski (Chi) | 21 | 1960 |
| | John Brodie (SF) | 21 | 1968 |
| | Rudy Bukich (Chi) | 21 | 1966 |
| | Ronnie Cahill (Chi.Cardinals) | 21 | 1943 |
| | Quincy Carter (Dal) | 21 | 2003 |
| | Kerry Collins (Car) | 21 | 1997 |
| | Irv Comp (GB) | 21 | 1944 |
| | Tim Couch (Cle) | 21 | 2001 |
| | Steve DeBerg (SF) | 21 | 1979 |
| | Craig Erickson (TB) | 21 | 1993 |
| | Brett Favre (GB) | 21 | 2003 |
| | John Grigas (Chi.Cardinals) | 21 | 1944 |
| | Steve Grogan (NE) | 21 | 1977 |
| | John Hadl (SD) | 21 | 1965 |
| | John Hadl (GB) | 21 | 1975 |
| | Sam Howell (Was) | 21 | 2023 |
| | Jack Jacobs (GB) | 21 | 1948 |
| | Ron Jaworski (Phi) | 21 | 1977 |
| | Brad Johnson (TB) | 21 | 2003 |
| | Charley Johnson (StL.Cardinals) | 21 | 1963 |
| | Randy Johnson (Atl) | 21 | 1966 |
| | Randy Johnson (Atl) | 21 | 1967 |
| | Bert Jones (Bal.Colts) | 21 | 1980 |
| | Dave Krieg (Az) | 21 | 1995 |
| | Bobby Layne (Det) | 21 | 1953 |
| | Bobby Layne (Pit) | 21 | 1959 |
| | Johnny Lujack (Chi) | 21 | 1950 |
| | Archie Manning (NO) | 21 | 1972 |
| | Dan Marino (Mia) | 21 | 1985 |
| | Baker Mayfield (Cle) | 21 | 2019 |
| | Hugh McCullough (Chi.Cardinals) | 21 | 1940 |
| | Warren Moon (Hou.Oilers) | 21 | 1991 |
| | Warren Moon (Hou.Oilers) | 21 | 1993 |
| | Craig Morton (Dal) | 21 | 1972 |
| | Joe Namath (NYJ) | 21 | 1972 |
| | Dan Pastorini (Hou.Oilers) | 21 | 1971 |
| | Jake Plummer (Az) | 21 | 2000 |
| | Philip Rivers (SD) | 21 | 2016 |
| | Geno Smith (NYJ) | 21 | 2013 |
| | Norm Snead (Phi) | 21 | 1968 |
| | Cliff Stoudt (Pit) | 21 | 1983 |
| | Fran Tarkenton (NYG) | 21 | 1971 |
| | Bobby Thomason (Phi) | 21 | 1956 |
| | Jack Thompson (TB) | 21 | 1983 |
| | Frank Tripucka (Den) | 21 | 1961 |
| | Bill Troup (Bal.Colts) | 21 | 1978 |
| | Norm Van Brocklin (LAR) | 21 | 1954 |
| | Norm Van Brocklin (LAR) | 21 | 1957 |
| | Marc Wilson (LA.Raiders) | 21 | 1985 |
| 216 | Steve Bartkowski (Atl) | 20 | 1979 |
| | Terry Bradshaw (Pit) | 20 | 1978 |
| | Dave Brown (NYG) | 20 | 1996 |
| | Ed Brown (Pit) | 20 | 1963 |
| | Mark Brunell (Jax) | 20 | 1996 |
| | Kerry Collins (Oak) | 20 | 2004 |
| | Charlie Conerly (NYG) | 20 | 1949 |
| | Andy Dalton (Cin) | 20 | 2013 |
| | Glenn Dobbs (LA.Dons) | 20 | 1948 |
| | Vince Evans (Chi) | 20 | 1981 |
| | Jim Everett (LAR) | 20 | 1991 |
| | Joe Ferguson (Buf) | 20 | 1981 |
| | Dan Fouts (SD) | 20 | 1978 |
| | Dan Fouts (SD) | 20 | 1985 |
| | Johnny Gildea (Pit) | 20 | 1935 |
| | Otto Graham (Cle) | 20 | 1950 |
| | Steve Grogan (NE) | 20 | 1976 |
| | Steve Grogan (NE) | 20 | 1979 |
| | Rex Grossman (Chi) | 20 | 2006 |
| | Rex Grossman (Was) | 20 | 2011 |
| | Jim Hart (StL.Cardinals) | 20 | 1977 |
| | Jim Hart (StL.Cardinals) | 20 | 1979 |
| | Jim Hart (StL.Cardinals) | 20 | 1980 |
| | Ron Jaworski (Phi) | 20 | 1981 |
| | Ron Jaworski (Phi) | 20 | 1985 |
| | Charley Johnson (StL.Cardinals) | 20 | 1962 |
| | Bert Jones (Bal.Colts) | 20 | 1981 |
| | Jack Kemp (Buf) | 20 | 1963 |
| | Jon Kitna (Det) | 20 | 2007 |
| | Dave Krieg (Sea) | 20 | 1985 |
| | Dave Krieg (Sea) | 20 | 1989 |
| | Dave Krieg (Sea) | 20 | 1990 |
| | Daryle Lamonica (Oak) | 20 | 1967 |
| | Bobby Layne (Det) | 20 | 1952 |
| | Jacky Lee (Den) | 20 | 1964 |
| | Clyde LeForce (Det) | 20 | 1947 |
| | Chuck Long (Det) | 20 | 1987 |
| | Don Majkowski (GB) | 20 | 1989 |
| | Archie Manning (NO) | 20 | 1975 |
| | Archie Manning (NO) | 20 | 1979 |
| | Archie Manning (NO) | 20 | 1980 |
| | Eli Manning (NYG) | 20 | 2007 |
| | Rick Mirer (Sea) | 20 | 1995 |
| | Craig Morton (NYG) | 20 | 1976 |
| | Ken O’Brien (NYJ) | 20 | 1986 |
| | Carson Palmer (Cin) | 20 | 2007 |
| | Carson Palmer (Cin) | 20 | 2010 |
| | Babe Parilli (Bos.Patriots) | 20 | 1966 |
| | Mike Phipps (Cle) | 20 | 1973 |
| | Jake Plummer (Az) | 20 | 1998 |
| | Jake Plummer (Az) | 20 | 2002 |
| | Jake Plummer (Den) | 20 | 2004 |
| | Milt Plum (Det) | 20 | 1962 |
| | George Ratterman (Buf) | 20 | 1947 |
| | Philip Rivers (SD) | 20 | 2011 |
| | Philip Rivers (LAC) | 20 | 2019 |
| | Tobin Rote (GB) | 20 | 1951 |
| | Mark Sanchez (NYJ) | 20 | 2009 |
| | Bud Schwenk (Bal.Colts) | 20 | 1947 |
| | Dennis Shaw (Buf) | 20 | 1970 |
| | Phil Simms (NYG) | 20 | 1985 |
| | Frankie Sinkwich (Det) | 20 | 1943 |
| | Frankie Sinkwich (Det) | 20 | 1944 |
| | Norm Snead (Phi) | 20 | 1970 |
| | Ken Stabler (Oak) | 20 | 1977 |
| | Matthew Stafford (Det) | 20 | 2009 |
| | Vinny Testaverde (Dal) | 20 | 2004 |
| | Joe Theismann (Was) | 20 | 1981 |
| | Bobby Thomason (Phi) | 20 | 1953 |
| | Y.A. Tittle (NYG) | 20 | 1962 |
| | Johnny Unitas (Bal.Colts) | 20 | 1969 |
| | Norm Van Brocklin (Phi) | 20 | 1958 |
| | Jim Zorn (Sea) | 20 | 1978 |
| | Jim Zorn (Sea) | 20 | 1980 |
