| No. | Quarterback | Equipo | Yardas | Temporada |
|---|---|---|---|---|
| 1 | Peyton Manning | Broncos | 5,477 | 2013 |
| 2 | Drew Brees | Saints | 5,476 | 2011 |
| 3 | Tom Brady | Buccaneers | 5,316 | 2021 |
| 4 | Patrick Mahomes | Chiefs | 5,250 | 2022 |
| 5 | Tom Brady | Patriots | 5,235 | 2011 |
| 6 | Drew Brees | Saints | 5,208 | 2016 |
| 7 | Drew Brees | Saints | 5,177 | 2012 |
| 8 | Drew Brees | Saints | 5,162 | 2013 |
| 9 | Ben Roethlisberger | Steelers | 5,129 | 2018 |
| 10 | Jameis Winston | Buccaneers | 5,109 | 2019 |
| 11 | Patrick Mahomes | Chiefs | 5,097 | 2018 |
| 12 | Dan Marino | Dolphins | 5,084 | 1984 |
| 13 | Drew Brees | Saints | 5,069 | 2008 |
| 14 | Matthew Stafford | Lions | 5,038 | 2011 |
| 15 | Justin Herbert | Chargers | 5,014 | 2021 |
| 16 | Matthew Stafford | Lions | 4,967 | 2012 |
| 17 | Drew Brees | Saints | 4,952 | 2014 |
| Ben Roethlisberger | Steelers | 4,952 | 2014 | |
| 19 | Matt Ryan | Falcons | 4,944 | 2016 |
| 20 | Eli Manning | Giants | 4,933 | 2011 |
| 21 | Matt Ryan | Falcons | 4,924 | 2018 |
| 22 | Joe Burrow | Bengals | 4,918 | 2024 |
| 23 | Kirk Cousins | Redskins | 4,917 | 2016 |
| 24 | Tony Romo | Cowboys | 4,903 | 2012 |
| 25 | Dak Prescott | Cowboys | 4,902 | 2019 |
| 26 | Matthew Stafford | Rams | 4,886 | 2021 |
| 27 | Drew Brees | Saints | 4,870 | 2015 |
| 28 | Patrick Mahomes | Chiefs | 4,839 | 2021 |
| 29 | Kurt Warner | Rams | 4,830 | 2001 |
| 30 | Tom Brady | Patriots | 4,827 | 2012 |
| 31 | Deshaun Watson | Texans | 4,823 | 2020 |
| 32 | Tom Brady | Patriots | 4,806 | 2007 |
| 33 | Derek Carr | Raiders | 4,804 | 2021 |
| 34 | Dan Fouts+ | Chargers | 4,802 | 1981 |
| 35 | Philip Rivers | Chargers | 4,792 | 2015 |
| 36 | Tom Brady | Patriots | 4,770 | 2015 |
| Matt Schaub | Texans | 4,770 | 2009 | |
| 38 | Andrew Luck | Colts | 4,761 | 2014 |
| 39 | Dan Marino+ | Dolphins | 4,746 | 1986 |
| 40 | Patrick Mahomes | Chiefs | 4,740 | 2020 |
| 41 | Justin Herbert | Chargers | 4,739 | 2022 |
| 42 | Peyton Manning+ | Broncos | 4,727 | 2014 |
| 43 | Matt Ryan | Falcons | 4,719 | 2012 |
| 44 | Daunte Culpepper | Vikings | 4,717 | 2004 |
| 45 | Dan Fouts+ | Chargers | 4,715 | 1980 |
| 46 | Philip Rivers | Chargers | 4,710 | 2010 |
| 47 | Matthew Stafford | Rams | 4,707 | 2025 |
| 48 | Peyton Manning+ | Colts | 4,700 | 2010 |
| 49 | Tom Brady | Buccaneers | 4,694 | 2022 |
| Matt Ryan | Falcons | 4,694 | 2014 | |
| 51 | Warren Moon+ | Oilers | 4,690 | 1991 |
| 52 | Rich Gannon | Raiders | 4,689 | 2002 |
| Warren Moon+ | Oilers | 4,689 | 1990 | |
| 54 | Jared Goff | Rams | 4,688 | 2018 |
| 55 | Carson Palmer | Cardinals | 4,671 | 2015 |
| 56 | Peyton Manning+ | Broncos | 4,659 | 2012 |
| 57 | Matthew Stafford | Lions | 4,650 | 2013 |
| 58 | Aaron Rodgers | Packers | 4,643 | 2011 |
| 59 | Jared Goff | Rams | 4,638 | 2019 |
| 60 | Tom Brady | Buccaneeers | 4,633 | 2020 |
| 61 | Jared Goff | Lions | 4,629 | 2024 |
| 62 | Philip Rivers | Chargers | 4,624 | 2011 |
| Tua Tagovailoa | Dolphins | 4,624 | 2023 | |
| 64 | Drew Brees+ | Saints | 4,620 | 2010 |
| 65 | Philip Rivers | Chargers | 4,615 | 2019 |
| 66 | Neil Lomax | Cardinals | 4,614 | 1984 |
| 67 | Joe Burrow | Bengals | 4,611 | 2021 |
| 68 | Andrew Luck | Colts | 4,593 | 2018 |
| 69 | Trent Green | Chiefs | 4,591 | 2004 |
| Matt Ryan | Falcons | 4,591 | 2015 | |
| 71 | Kurt Warner+ | Cardinals | 4,583 | 2008 |
| 72 | Matt Ryan | Falcons | 4,581 | 2020 |
| 73 | Tom Brady | Patriots | 4,577 | 2017 |
| 74 | Jared Goff | Lions | 4,575 | 2023 |
| 75 | Jared Goff | Lions | 4,564 | 2025 |
| 76 | Peyton Manning+ | Colts | 4,557 | 2004 |
| 77 | Drew Bledsoe | Patriots | 4,555 | 1994 |
| 78 | Dak Prescott | Cowboys | 4,552 | 2025 |
| 79 | Kirk Cousins | Vikings | 4,547 | 2022 |
| 80 | Josh Allen | Bills | 4,544 | 2020 |
| 81 | Jay Cutler | Broncos | 4,526 | 2008 |
| 82 | Dak Prescott | Cowboys | 4,516 | 2023 |
| 83 | Philip Rivers | Chargers | 4,515 | 2017 |
| Matt Ryan | Falcons | 4,515 | 2013 | |
| 85 | Peyton Manning+ | Colts | 4,500 | 2009 |
| Baker Mayfield | Buccaneers | 4,500 | 2024 |
Todas las temporadas de 4,500 yardas o más