| No. | Quarterback (Equipo) | Touchdowns | Temporada |
|---|---|---|---|
| 1 | Peyton Manning (Den) | 55 | 2013 |
| 2 | Tom Brady (NE) | 50 | 2007 |
| Patrick Mahomes (KC) | 50 | 2018 | |
| 4 | Peyton Manning (Ind) | 49 | 2004 |
| 5 | Dan Marino (Mia) | 48 | 1984 |
| Aaron Rodgers (GB) | 48 | 2020 | |
| 7 | Drew Brees (NO) | 46 | 2011 |
| 8 | Aaron Rodgers (GB) | 45 | 2011 |
| 9 | Dan Marino (Mia) | 44 | 1986 |
| 10 | Tom Brady (TB) | 43 | 2021 |
| Drew Brees (NO) | 43 | 2012 | |
| Joe Burrow (Cin) | 43 | 2024 | |
| 13 | Lamar Jackson (Bal) | 41 | 2024 |
| Patrick Mahomes (KC) | 41 | 2022 | |
| Baker Mayfield (TB) | 41 | 2024 | |
| Matthew Stafford (Det) | 41 | 2011 | |
| Matthew Stafford (LAR) | 41 | 2021 | |
| Kurt Warner (SLR) | 41 | 1999 | |
| 19 | Tom Brady (TB) | 40 | 2020 |
| Andrew Luck (Ind) | 40 | 2014 | |
| Aaron Rodgers (GB) | 40 | 2016 | |
| Russell Wilson (Sea) | 40 | 2020 | |
| 23 | Tom Brady (NE) | 39 | 2011 |
| Drew Brees (NO) | 39 | 2013 | |
| Daunte Culpepper (Min) | 39 | 2004 | |
| Brett Favre (GB) | 39 | 1996 | |
| Andrew Luck (Ind) | 39 | 2018 | |
| Peyton Manning (Den) | 39 | 2014 | |
| Aaron Rodgers (GB) | 39 | 2012 | |
| 30 | Brett Favre (GB) | 38 | 1995 |
| Justin Herbert (LAC) | 38 | 2021 | |
| Patrick Mahomes (KC) | 38 | 2020 | |
| Aaron Rodgers (GB) | 38 | 2014 | |
| Matt Ryan (Atl) | 38 | 2016 | |
| 35 | Josh Allen (Buf) | 37 | 2020 |
| Drew Brees (NO) | 37 | 2016 | |
| Jared Goff (Det) | 37 | 2024 | |
| Patrick Mahomes (KC) | 37 | 2021 | |
| Peyton Manning (Den) | 37 | 2012 | |
| Dak Prescott (Dal) | 37 | 2021 | |
| Aaron Rodgers (GB) | 37 | 2021 | |
| 42 | Josh Allen (Buf) | 36 | 2021 |
| Steve Beuerlein (Car) | 36 | 1999 | |
| George Blanda (Hou.Oilers) | 36 | 1961 | |
| Tom Brady (NE) | 36 | 2010 | |
| Tom Brady (NE) | 36 | 2015 | |
| Lamar Jackson (Bal) | 36 | 2019 | |
| Dak Prescott (Dal) | 36 | 2023 | |
| Tony Romo (Dal) | 36 | 2007 | |
| Y.A. Tittle (NYG) | 36 | 1963 | |
| Kurt Warner (SLR) | 36 | 2001 | |
| Steve Young (SF) | 36 | 1998 | |
| 53 | Josh Allen (Buf) | 35 | 2022 |
| Blake Bortles (Jax) | 35 | 2015 | |
| Joe Burrow (Cin) | 35 | 2022 | |
| Kirk Cousins (Min) | 35 | 2020 | |
| Sam Darnold (Min) | 35 | 2024 | |
| Brett Favre (GB) | 35 | 1997 | |
| Eli Manning (NYG) | 35 | 2015 | |
| Cam Newton (Car) | 35 | 2015 | |
| Carson Palmer (Az) | 35 | 2015 | |
| Matt Ryan (Atl) | 35 | 2018 | |
| Russell Wilson (Sea) | 35 | 2018 | |
| Steve Young (SF) | 35 | 1994 | |
| 65 | Tom Brady (NE) | 34 | 2012 |
| Drew Brees (NO) | 34 | 2008 | |
| Drew Brees (NO) | 34 | 2009 | |
| Joe Burrow (Cin) | 34 | 2021 | |
| Randall Cunningham (Min) | 34 | 1998 | |
| Daryle Lamonica (Oak) | 34 | 1969 | |
| Philip Rivers (SD) | 34 | 2008 | |
| Ben Roethlisberger (Pit) | 34 | 2018 | |
| Tony Romo (Dal) | 34 | 2014 | |
| Russell Wilson (Sea) | 34 | 2015 | |
| Russell Wilson (Sea) | 34 | 2017 | |
| 76 | Tom Brady (NE) | 33 | 2014 |
| Drew Brees (NO) | 33 | 2010 | |
| Drew Brees (NO) | 33 | 2014 | |
| Kirk Cousins (Min) | 33 | 2021 | |
| Daunte Culpepper (Min) | 33 | 2000 | |
| Andy Dalton (Cin) | 33 | 2013 | |
| Brett Favre (GB) | 33 | 1994 | |
| Brett Favre (Min) | 33 | 2009 | |
| Dan Fouts (SD) | 33 | 1981 | |
| Jim Kelly (Buf) | 33 | 1991 | |
| Peyton Manning (Ind) | 33 | 2000 | |
| Peyton Manning (Ind) | 33 | 2009 | |
| Peyton Manning (Ind) | 33 | 2010 | |
| Warren Moon (Hou) | 33 | 1990 | |
| Warren Moon (Min) | 33 | 1995 | |
| Philip Rivers (SD) | 33 | 2016 | |
| Ben Roethlisberger (Pit) | 33 | 2020 | |
| Ryan Tannehill (Ten) | 33 | 2020 | |
| Vinny Testaverde (Bal) | 33 | 1996 | |
| Y.A. Tittle (NYG) | 33 | 1962 | |
| Deshaun Watson (Hou) | 33 | 2020 | |
| Carson Wentz (Phi) | 33 | 2017 | |
| Jameis Winston (TB) | 33 | 2019 | |
| 99 | Tom Brady (NE) | 32 | 2017 |
| Drew Brees (NO) | 32 | 2015 | |
| Drew Brees (NO) | 32 | 2018 | |
| Derek Carr (Oak) | 32 | 2015 | |
| Lynn Dickey (GB) | 32 | 1983 | |
| Brett Favre (GB) | 32 | 2001 | |
| Brett Favre (GB) | 32 | 2003 | |
| Jeff Garcia (SF) | 32 | 2001 | |
| Jared Goff (LAR) | 32 | 2018 | |
| Sonny Jurgensen (Phi) | 32 | 1961 | |
| Dave Krieg (Sea) | 32 | 1984 | |
| Jordan Love (GB) | 32 | 2023 | |
| Scott Mitchell (Det) | 32 | 1995 | |
| Carson Palmer (Cin) | 32 | 2005 | |
| Philip Rivers (SD) | 32 | 2013 | |
| Philip Rivers (LAC) | 32 | 2018 | |
| Ben Roethlisberger (Pit) | 32 | 2007 | |
| Ben Roethlisberger (Pit) | 32 | 2014 | |
| Matt Ryan (Atl) | 32 | 2012 | |
| Matthew Stafford (Det) | 32 | 2015 | |
| Johnny Unitas (Bal) | 32 | 1959 | |
| 120 | Steve Bartkowski (Atl) | 31 | 1980 |
| Jim Everett (LAR) | 31 | 1988 | |
| Brett Favre (GB) | 31 | 1998 | |
| Ryan Fitzpatrick (NYJ) | 31 | 2015 | |
| Jeff Garcia (SF) | 31 | 2000 | |
| Justin Herbert (LAC) | 31 | 2020 | |
| Sonny Jurgensen (Was) | 31 | 1967 | |
| Andrew Luck (Ind) | 31 | 2016 | |
| Eli Manning (NYG) | 31 | 2010 | |
| Peyton Manning (Ind) | 31 | 2006 | |
| Peyton Manning (Ind) | 31 | 2007 | |
| Donovan McNabb (Phi) | 31 | 2004 | |
| Joe Montana (SF) | 31 | 1987 | |
| Babe Parilli (Bos) | 31 | 1964 | |
| Brock Purdy (SF) | 31 | 2023 | |
| Philip Rivers (SD) | 31 | 2014 | |
| Aaron Rodgers (GB) | 31 | 2015 | |
| Tony Romo (Dal) | 31 | 2011 | |
| Tony Romo (Dal) | 31 | 2013 | |
| Russell Wilson (Sea) | 31 | 2019 | |
| 140 | Steve Bartkowski (Atl) | 30 | 1981 |
| John Brodie (SF) | 30 | 1965 | |
| Kirk Cousins (Min) | 30 | 2018 | |
| Randall Cunningham (Phi) | 30 | 1990 | |
| Len Dawson (KC) | 30 | 1964 | |
| Brett Favre (GB) | 30 | 2004 | |
| Vince Ferragamo (LAR) | 30 | 1980 | |
| Dan Fouts (SD) | 30 | 1980 | |
| Jared Goff (Det) | 30 | 2023 | |
| Daryle Lamonica (Oak) | 30 | 1967 | |
| Eli Manning (NYG) | 30 | 2014 | |
| Dan Marino (Mia) | 30 | 1985 | |
| Dan Marino (Mia) | 30 | 1994 | |
| Dak Prescott (Dal) | 30 | 2019 | |
| Philip Rivers (SD) | 30 | 2010 | |
| Aaron Rodgers (GB) | 30 | 2009 | |
| Brian Sipe (Cle) | 30 | 1980 | |
| Geno Smith (Sea) | 30 | 2022 | |
| Kurt Warner (Az) | 30 | 2008 |
