| América | 13 | 1965-66, 1970-71, 1975-76, 1983-84, 1984-85, P-1985, 1987-88, 1988-89, V-2002, C-2005, C-2013, A-2014 y A-2018 |
| Guadalajara | 12 | 1956-57, 1958-59, 1959-60, 1960-61, 1961-62, 1963-64, 1964-65, 1969-70, 1986-87, V-1997, A-2006 y C-2017 |
| Toluca | 10 | 1966-67, 1967-68, 1974-75, V-1998, V-1999, V-2000, A-2002, A-2005, A-2008 y B-2010 |
| Cruz Azul | 9 | 1968-69, M-1970, 1971-72, 1972-73, 1973-74, 1978-79, 1979-80, I-1997 y G-2021 |
| León | 8 | 1947-48, 1948-49, 1951-52, 1955-56, 1991-92, A-2013, C-2014 y G-2020 |
| Pumas UNAM | 7 | 1976-77, 1980-81, 1990-91, C-2004, A-2004, C-2009 y C-2011 |
| Tigres UANL | 7 | 1977-78, 1981-82, A-2011, A-2015, A-2016, A-2017 y C-2019 |
| Pachuca | 7 | I-1999, I-2001, A-2003, C-2006, C-2007, C-2016, A-2022 |
| Santos Laguna | 6 | I-1996, V-2001, C-2008, C-2012, C-2015 y C-2018 |
| Monterrey | 5 | M-1986, C-2003, A-2009, A-2010 y A-2019 |
| Atlante | 3 | 1946-47, 1992-93 y A-2007 |
| Necaxa | 3 | 1994-95, 1995-96 e I-1998 |
| Atlas | 3 | 1950-51, A-2021 y C-2022 |
| Puebla | 2 | 1982-83 y 1989-90 |
| Zacatepec | 2 | 1954-55 y 1957-58 |
| Veracruz | 2 | 1945-46 y 1949-50 |
| Oro | 1 | 1962-63 |
| Monarcas Morelia | 1 | I-2000 |
| Club España | 1 | 1944-45 |
| Tecos UAG | 1 | 1993-94 |
| Club Asturias | 1 | 1943-44 |
| Tampico | 1 | 1952-53 |
| Club Marte | 1 | 1953-54 |
| Tijuana | 1 | A-2012 |
