ESTADÍSTICAS NFL
| No. | Jugador | Equipo | Pick-6 | Fecha | Rival |
|---|
| 1 | Bill Blackburn | Cardinals | 2 | 1948-10-24 | Boston Yanks |
| | Dan Sandifer | Redskins | 2 | 1948-10-31 | Boston Yanks |
| | Bobby Franklin | Browns | 2 | 1960-12-11 | Bears |
| | Billy Stacy | Rams | 2 | 1961-11-05 | Cowboys |
| | Jerry Norton | Rams | 2 | 1961-11-26 | Steelers |
| | Miller Farr | Oilers | 2 | 1968-12-07 | Bills |
| | Ken Houston+ | Oilers | 2 | 1971-12-19 | Chargers |
| | Jim Kearney | Chiefs | 2 | 1972-10-01 | Broncos |
| | Lemar Parrish | Bengals | 2 | 1972-12-17 | Oilers |
| | Dick Anderson | Dolphins | 2 | 1973-12-03 | Steelers |
| | Prentice McCray | Patriots | 2 | 1976-11-21 | Jets |
| | Kenny Johnson | Falcons | 2 | 1983-11-27 | Packers |
| | Mike Kozlowski | Dolphins | 2 | 1983-12-16 | Jets |
| | Dave Brown | Seahawks | 2 | 1984-11-04 | Chiefs |
| | Lloyd Burruss | Chiefs | 2 | 1986-10-19 | Chargers |
| | Henry Jones | Bills | 2 | 1992-09-20 | Colts |
| | Robert Massey | Cardinals | 2 | 1992-10-04 | Redskins |
| | Eric Allen+ | Eagles | 2 | 1993-12-26 | Saints |
| | Ken Norton Jr. | 49ers | 2 | 1995-10-22 | Rams |
| | Otis Smith | Jets | 2 | 1997-12-14 | Buccaneers |
| | Dewayne Washington | Steelers | 2 | 1998-11-22 | Jaguars |
| | Aaron Glenn | Texans | 2 | 2002-12-08 | Steelers |
| | Ronde Barber+ | Buccaneers | 2 | 2006-10-22 | Eagles |
| | Antrel Rolle | Cardinals | 2 | 2007-11-18 | Bengals |
| | Derrick Johnson | Chiefs | 2 | 2010-01-03 | Broncos |
| | David Bowens | Browns | 2 | 2010-10-24 | Saints |
| | Jackrabbit Jenkins | Rams | 2 | 2012-11-25 | Cardinals |
| | Zach Brown | Titans | 2 | 2012-12-30 | Jaguars |
| | Mike Edwards | Buccaneers | 2 | 2021-09-19 | Falcons |
| | Kenny Moore | Colts | 2 | 2023-11-05 | Panthers |
